The article uses the Quantitative Mass Spectrometry method to understand disease progression by integrating brain and Cerebrospinal Fluid proteome for early diagnostic development. There is a direct relationship between CSF to the brain, which helps develop better biomarkers to understand neuropathology.

AIM: To examine the relationships between variables (Age; Biomarkers: ABeta42,tTau, PTau; APOE gene; MoCA cognitive test) using correlation coefficients (Pearson correlation) to determine if there are any associations between age, biomarker levels, cognitive scores, and APOE gene.

Rstudio Link: Scientific data analysis